Although current study categorized as small cross-sectional study, while cannabis use may reduce pain and relieves from spasticity in multiple sclerosis (MS) patients, however, the result of current small study significantly showed that cannabis effects had adverse event of cognitive difficulties in that patients.
This findings appeared after the researchers compared the effects of cannabis use (smoked or ingested) in 25 patients with MS and 25 patients with MS without using cannabis.
All participants were well matched in terms of sex, IQ before diagnosis, level of education and disability, and no illicit drug used than cannabis (based on broad-spectrum urine drug screen). The average age of all particiants was 43 years old and had MS about 12 years.
Reported in Neurology on March 29, 2011, cannabis user had lower number of standard cognitive tests measuring visuospatial perception, executive functioning, and information processing speed, when compared to non cannabis user. This is including a classification of cognitively impaired that tested more than 12 hours after the last cannabis use.
Despite the cannabis user in this study doesn’t mean had MS before they use it, and some of them may possibly categorized as heavy cannabis user, the investigators noted that their findings replicates “the literature from the general population suggests, with few exception, that there are residual, adverse cognitive difficulties extending beyond this period,” and “point toward the detrimental effects of cannabis persisting beyond intoxication” in the cannabis users.