Healthcare
No matter how we manage our health, efficacy, risks and costing are top concernsFolic Acid does not exacerbates patients with B12 vitamin deficiency
There are many benefits from an essential water soluble B vitamin of folic acid such as in fight of bipolar disease, depression, reduce the risk of birth defect, increase red blood production, and much more.
However, because there were some cases of people with B12-vitamin deficiency suggested that high level of serum folate seem exacerbates their deficiency which indicated from having low hemoglobin (Hgb), raise of total homocysteine (tHcy), and elevated methylmalonic acid (MMA), therefore, the researchers investigated this negative relationship.
Reported in the American Journal of Clinical Nutrition on June 8, 201, the study authors said that folate acid does not exacerbates the people with B12-vitamin deficiency.
One of the study author and lead investigator, James L. Mills, MD, MS, from National Institute of Health, write in news release, “We fond no evidence that folate could worsen their health problems.”
According to their findings, consuming folic acid either from supplement or fortified food, and even resulting high amount of folate in their blood “does not seem to interfere with the body’s use of vitamin B12 in otherwise healthy individuals.”
The study involved 2,507 university students who were questionned about use of both in folic acid and B12 supplements, their medical history, and who gave blood samples for testing of serum and red cell folate, plasma homocysteine, hemoglobin, holotranscobalamin (holoTC), MMA, and ferritin in serum.
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