Bladder cancer is common cancer in the urinary tracts both male and female, and health problem related to reproductive male system.
In the U.S, most type of common bladder cancer occurs is Transitional Cell Carcinoma (TCC) which the cancer occur entire urinary tract, including ureter, renal pelvis, urethra and bladder itself.

In these condition, 90% tumors occur in the tissue layers that consisted approximately 3-7 cell layers within the muscular bladder.

Even the cancer less significant risk to the death, however for invasive cancer may categorized ‘lethal’ and possible for mortality.
An estimation in 2009, 70,980 new patients diagnosed with bladder cancer in the U.S, and 14,330 of them will die of the disease.

Common medical treatment often used such as Transurethral Resection (or TURP-Transurethral resection of the prostate) and periodic Endoscopy of the urinary bladder via urethra (Cystoscopy).

Another cancer in bladder is related to Schistosoma haematobium infection (schistosoma haematobium parasite) that lead to Squamous cell carcinomas (SCC) and other impact from present cancer itself such as Adenocarcinoma (cancer in glandular tissue).

Squamous cell carcinomas predicted about 5% in the U.S and 75% in the worldwide while Adenorcarcinoma contributed about less than 2% from total bladder cancer account.
Common medical treatment for Adenorcarcinoma such as Radical cystectomy, and for Squamous Cell Carcinoma with surgical and topical medication including external beam radiotherapy.

For rare condition, other nonurothelial primary bladder cancer may leads to;
- Small cell carcinoma
It’s heavy malignant cancer.
Although it’s very rare, it would be happened.
Medical treatment may including chemotherapy and radiotherapy with some their risks (hair loss, cognitive changes, radiation necrosis of the brain, headache).

- Primary lymphoma
Arise in the bladder submucosa.
Common medical treatment often used such as radiation therapy, chemotherapy and bone marrow transplantation.
The risks almost same with above mention.

- Carcinosarcoma
It’s combination of malignant tumor from epithelial tissue cancer and connective tissue cancer.
The medical treatment and risks almost same with above description.

- Sarcoma such as Leiomyosarcoma (smooth muscle connective tissue tumor) and Rhabdomyosarcoma (connective tissues cancer that arise from skeletal muscle progenitors and some any anatomic location which common occur in the children).
Instead Leiomyosarcoma very rare, it’s also unpredicted.
Medical treatment often used surgery procedure including chemotherapy and radiation additionally.
Both Leiomyosarcoma and Rhabdomyosarcoma using same medical treatment options (surgery, chemotherapy, radiotherapy) with all their side effects.

The symptoms of bladder cancer as following;
- Painless gross hematuria (blood in the urine)
- Pain and discomfort during urination (dysuria)
- urgency urination
- frequent urination
- pelvic pain
- bony pain
- flank pain

Most common causes of bladder cancer linked to environment exposure (aromatic amines in dyes, solvents, paints, leather dust, combustion products, inks, textile, rubber), smoking (50% contribution), side effects of medical treatment (radiation to pelvis treatment, chemotherapy, cyclophosphamide), spinal cord injuries from the effects of indwelling catheters, and hereditary factors related to family history.

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