Healthcare
No matter how we manage our health, efficacy, risks and costing are top concernsLatest treatment on prostate cancer by Croton Oil
According to the researchers from Rutgers University, an active ingredient found in the oil of the Southeast Asian croton plant–12-O-tetradecanoylphorbol-13-acetate, commonly known as TPA, may inhibit the growth of new prostate cancer cells.
One of the study authors, Allan Conney, PhD, said, “We demonstrated TPA could simultaneously stop the growth of new prostate cancer cells, kill existing cancer cells and ultimately shrink prostate tumors.”.
The researchers also tested the effect of TPA in combination with all-trans retinoic acid (ATRA), a vitamin A derivative that has been shown to effectively treat leukemia.
In the study, a mice with induced prostate tumors received a daily dose of TPA, ATRA or a combination of the two for 46 days.
After 21 days of treatment, tumor regression became apparent in 62 percent of mice treated with TPA, compared to 31 percent of mice treated with ATRA. All mice receiving the combination treatment showed signs of tumor regression.
Researchers also found TPA and the combination treatment continued to inhibit tumor growth for the duration of the study, compared to ATRA inhibiting tumor growth only for the first 28 days of treatment.
Published in the March issue of Cancer Research, Conney said, “Our studies are an important early step in a long process, and we are planning additional testing in humans.”, because further research with these compounds and others, could provide hope for the half million new cases of prostate cancer each year.
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Alfred said on Saturday, March 14, 2009, 18:16
I am very interested in this experiment. My father died of prostate cancer, and I can inherit him.
best wishes alfred