Have you ever seen a children looks dirty, but seem okay and sometime appear great performance?

In the current study, the researcher found that kids with too clean or over-sanitized can impact to disability of skin to heal and causing high risk of inflammation and disease.

The researchers from the School of Medicine at the University of California, San Diego found common normal bacterial species, staphylococci, that living in the skin when dirty can balancing immune response to protect the body when they get hurt.

How could this happened?

From the study, researcher found that this bactery can produce lipoteichoic acid (LTA) that acts as regulator of autolytic wall enzymes that keeps the keratinocytes in check and stop them from aggressive inflammatory response.
In other words, It has antigenic properties being able to stimulate specific immune response.

Professor Richard Gallo, lead of researcher said, “the exciting implication of the work is that if provides a molecular basis to understand the hygiene hypothesis and has uncovered elements of the wound repair response that were previously unknown. This may help us devise new therapeutic approaches for inflammatory skin disease.”

Many kids right now have severe from any allergy.
Despite genetic factor that influence the allergy, this result might be good considered to stop ‘campaign’ to the children for mollycoddled and over-sanitized.

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